Rachel Williams, "Surface Modification of Biomaterials: Methods, Analysis and Applications"
English | ISBN: 1845696409 | 2010 | PDF | 436 pages | 11,3 MB
The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a materialâ€™s surface can be tailored to improve biocompatibility, adhesion and cell interactions.
Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface Modification of Biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimize biological interactions and enhance clinical performance.
Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerization, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalization and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behavior and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analyzing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimize interactions with blood, control infection, optimize interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimize interactions with bone.
The distinguished editor and international team of contributors to Surface Modification of Biomaterials have produced a unique overview and detailed chapters on a range of surface modification techniques which will provide an excellent resource for biomaterials researchers and scientists and engineers concerned with improving the properties of biomaterials. It will also be beneficial for academics researching surface modification.
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